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Vaccines & Immunology
mRNA platforms, boosters, monoclonals, and immune‑system science.
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Amsbio expands range of high RNA quality FFPE tissue blocks
7+ hour, 53+ min ago (201+ words) Amsbio has expanded its range of high-quality FFPE tissues and controls designed to support biomarker discovery, histopathology, translational research and assay development. Although FFPE samples maintain tissue structure for histological analysis, RNA damage from fixation, embedding, and storage increases with…...
Immune Signal IL-18 Supercharges Rare T Cells for Solid Tumor Therapy
1+ hour, 46+ min ago (662+ words) Researchers report that adding interleukin-18 to cultures of scarce human Vδ1 T cells boosts their expansion, survival and antitumor performance in a lung cancer mouse model....
Thymosin Alpha-1: Immune Signaling and Molecular Research
3+ hour, 1+ min ago (121+ words) Published 4:48 pm Monday, October 12, 2026 Hypothesized Role in Immune System Signaling The diverse signaling interactions associated with Thymosin Alpha-1 have encouraged its exploration across numerous research platforms. Investigators interested in immune signaling mechanisms often employ peptides such as Thymosin Alpha-1 as…...
Dual-targeting siRNAs could treat more complex genetic diseases
3+ hour, 35+ min ago (1072+ words) An innovative bispecific siRNA design hits two genes at once, taking away one of cancer’s tricks for evading treatment. Some might say genetics research is in a rut. Biologists have made incredible biological and therapeutic discoveries over the past several…...
Preparing for Unknown Viruses With Adjuvant-Based Immune Boosting
7+ hour, 30+ min ago (10+ words) Technology Networks...
Sensible hands mRNA production back to the cell
5+ hour, 8+ min ago (217+ words) “The field still relies largely on synthetic manufacturing technology developed more than 40 years ago,” said Miroslav Gasparek, Sensible’s co-founder and CEO. “We are taking a fundamentally different approach, using living cells to produce naturally modified mRNA while reducing the cost…...
Injectable Seaweed Hydrogel Powered by Bimetallic Nanozymes Turns Pancreatic Tumors Into Immune Training Grounds
2+ hour, 34+ min ago (47+ words) A marine polysaccharide hydrogel loaded with a zinc-iron MOF nanozyme and glucose oxidase induces ferroptosis and activates cGAS-STING immunity to suppress pancreatic tumors in mice. News Source: Nathaniel Bowman. (October 12, 2026). Injectable Seaweed Hydrogel Powered by Bimetallic Nanozymes Turns Pancreatic Tumors…...
Dual-Target Antibody Strikes Two Inflammatory Pathways to Ease Colitis in Mice
2+ hour, 17+ min ago (680+ words) Scientists have engineered a bispecific antibody that simultaneously blocks TL1A and IL-12/23p40, suppressing pathogenic Th1/Th17 immune responses and significantly ameliorating colitis in humanized mice....
PacBio and TychoBio partner to advance AI-driven RNA therapies
10+ hour, 41+ min ago (345+ words) PacBio and AI drug discovery company TychoBio have announced a collaboration to generate large-scale full-length RNA datasets to support the development of new RNA therapies for rare diseases. The companies plan to use PacBio HiFi sequencing and Kinnex long-read RNA…...
HILIC VS RP: Separating Impurities in Fatty-Acid-Conjugated siRNAs (Part 2)
7+ hour, 53+ min ago (209+ words) LCGC International provides separation science insights, including liquid chromatography (HPLC), gas chromatography (GC), and mass spectrometry (MS). At ISC 2026 in Prague, Czech Republic, a session on the analysis of nucleic acids and oligonucleotides featured Martina Lioi of Novartis Pharma AG,…...